For a complete listing, you can also check here (Google Scholar) or here (Pubmed).
2024
Li VL, Xiao S, Schlosser P, Scherer N, Wiggenhorn AL, Karoly ED, Köttgen A, Long JZ.
SLC17 transporters mediate renal excretion of Lac-Phe in mice and humans
[Submitted]
bioRxiv
Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, Cavanagh PE, Zeng X, Rajniak J, Lu N, Xiao S, Zhao M, Moya-Garzon MD, Truong SD, Chou JCC, Wat LW, Chidambaranathan-Reghupaty S, Coassolo L, Xu D, Shen F, Huang W, Ramirez CB, Jang C, Svensson KJ, Fischbach MA, Long JZ.
A PTER-dependent pathway of taurine metabolism linked to energy balance.
bioRxiv
Xiao S, Li VL, Lyu X, Chen X, Wei W, Abbasi F, Knowles JW, Deng S, Tiwari G, Shi X, Zheng S, Farrell L, Chen ZZ, Taylor KD, Guo X, Goodarzi MO, Wood AC, Ida Chen YD, Lange LA, Rich SS, Rotter JI, Clish CB, Tahir UA, Gerszten RE, Benson MD, Long JZ.
Lac-Phe mediates the effects metformin on food intake and body weight.
Nat Metab. 2024 Mar 18 [in press]
bioRxiv
Press: BioWorld, Science Daily, MSN, Science Blog, Tech Explorist, Technology Networks, Medical News Today, GEN, Very Well Health
Science Press: Nature Metabolism News & Views, Nature Reviews Endocrinology Research Highlight, Stanford Medicine News Center, Trinity College Dublin Featured
Liu S, Ezran C, Wang MFZ, Li Z, The Tabula Microcebus Consortium, Long JZ, Vlaminck ID, Wang S, Kuo C, Epelbaum J, Terrien J, Krasnow MA, Ferrell JE.
An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome.
Nat Commun. 2024 Mar 11;15(1):2188
bioRxiv
Lone JB, Long JZ, Svensson KJ.
Size matters: the biochemical logic of ligand type in endocrine crosstalk.
Life Metab. 2024 Feb;3(1).
Wei W, Raun S, Long JZ.
Molecular insights from multi-omic studies of physical activity.
Diabetes 2024 Feb 1;73(2):162-168
2023
Alvarez-Buylla A, Moya-Garzon MD, Rangel AE, Tapia EE, Tanzo JT, Soh HT, Coloma LA, Long JZ, O’Connell LA.
Binding and sequestration of poison frog alkaloids by a plasma globulin.
Elife 2023 Dec 19:12:e85096
bioRxiv
Wiggenhorn AL, Abuzaid HZ, Coassolo L, Li VL, Tanzo JT, Wei W, Lyu X, Svensson KJ, Long JZ.
A class of secreted mammalian peptides with potential to expand cell-cell communication.
Nat Commun. 2023 Dec 8;14(1):8125.
bioRxiv
Rodencal J, Kim N, He A, Li VL, Lange M, He J, Tarangelo A, Schafer ZT, Olzmann JA, Long JZ, Sage J, Dixon SJ. Sensitization of cancer cells to ferroptosis coincident with cell cycle arrest.
Cell Chem. Biol. 2023 Nov 9:S2451-9456(23)00372-0.
bioRxiv
Møller LLV, Ali MS, Davey J, Raun SH, Andersen NR, Long JZ, Qian H, Jeppesen JF, Henriquez-Olguin C, Frank E, Jensen TE, Højlund K, Wojtaszewski JFP, Nielsen J, Chiu TT, Jedrychowski MP, Gregorevic P, Klip A, Richter EA, Sylow L.
The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action.
Proc Natl Acad Sci U S A. 2023 Jul 4;120(27):e2211041120.
Wei W, Riley NM, Lyu X, Shen X, Guo J, Raun SH, Zhao M, Moya-Garzon MD, Basu H, Sheng-Hwa Tung A, Li VL, Huang W, Wiggenhorn AL, Svensson KJ, Snyder MP, Bertozzi CR, Long JZ.
Organism-wide, cell-type-specific secretome mapping of exercise training in mice.
Cell Metab. 2023 Jul 11;35(7):1261-1279.e11.
bioRxiv
Press: Science Signaling Editors’ Choice; The Scientist News & Opinion
Tanzo JT, Li VL, Wiggenhorn AL, Moya-Garzon MD, Wei W, Lyu X, Dong W, Tahir UA, Chen ZZ, Cruz DE, Deng S, Shi X, Zheng S, Guo Y, Sims M, Abu-Remaileh M, Wilson JG, Gerszten RE, Long JZ, Benson MD.
CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels.
J Biol Chem. 2023 Jun;299(6):104764.
bioRxiv
Saxton RA, Caveney NA, Moya-Garzon MD, Householder KD, Rodriguez GE, Burdsall KA, Long JZ, Garcia KC.
Structural insights into the mechanism of leptin receptor activation.
Nat Commun. 2023 Mar 31;14(1):1797.
2022
Wang Y, Leung VH, Zhang Y, Nudell VS, Loud M, Servin-Vences MR, Yang D, Wang K, Moya-Garzon MD, Li VL, Long JZ, Patapoutian A, Ye L.
The role of somatosensory innervation of adipose tissues.
Nature 2022 Sep;609(7927):569-574.
Li VL, He Y, Contrepois K, Liu H, Kim JT, Wiggenhorn AM, Tanzo JT, Tung AS, Lyu X, Zushin PH, Jansen RS, Michael B, Loh KY, Yang AC, Carl CS, Voldstedlund CT, Wei W, Terrell SM, Moeller BC, Arthur RM, Wallis GA, Wetering K, Stahl A, Kiens B, Richter EA, Banik SM, Snyder MP, Xu Y, Long JZ.
An exercise-inducible metabolite that suppresses feeding and obesity.
Nature 2022 Jun;606(7915):785-790.
Press: New York Times, Yahoo! News, Fox News, MSN, Daily Mail UK, Fierce Biotech, NewScientist, ScienceDaily, Cosmos Magazine, Technology Networks, BioSpace, Euronews, La Vanguardia, Today UK News, SciTechDaily, Genetic Engineering & Biotechnology News
Science Press: Nature News & Views, Science News, C&EN, Stanford Medicine News, UC Davis News, Baylor College of Medicine News, Radboud University News, Netherlands Cancer Institute News
Media: 90 seconds with Lisa Kim
Long JZ.
Molecular transducers at the cardiometabolic benefits of exercise.
Nat. Rev. Endo. 2022 Feb;18(2):77-78.
Tarangelo A, Rodencal J, Kim JT, Magtanong L, Long JZ, Dixon SJ.
Nucleotide biosynthesis links glutathione metabolism to ferroptosis sensitivity.
Life Sci Alliance. 2022 Jan 24;5(4):e202101157.
2021
Wei W,* Riley NM,* Lyu X, Bertozzi CR, Long JZ.
Protocol for cell type-specific labeling, enrichment, and proteomic profiling of plasma proteins in mice.
STAR Protoc. 2021 Dec 11;2(4):101014. *equal contribution
Babin BM, Keller LJ, Pinto Y, Li VL, Eneim AS, Vance SE, Terrell SM, Bhatt AS, Long JZ, Bogyo M.
Identification of covalent inhibitors that disrupt M. tuberculosis growth by targeting multiple serine hydrolases involved in lipid metabolism.
Cell Chem. Biol. 2021 Sep 20;S2451.
Onguka O, Babin BM, Lakemeyer M, Foe IT, Amara N, Terrell SM, Lum KM, Cieplak P, Niphakis MJ, Long JZ, Bogyo M.
Toxoplasma gondii serine hydrolases regulate parasite lipid mobilization during growth and replication within the host.
Cell Chem. Biol. 2021 Oct 21;28(10):1501.
Ngo D, Benson MD, Long JZ, Chen ZZ, Wang R, Nath AK, Keyes MJ, Shen D, Sinha S, Kuhn E, Morningstar JE, Shi X, Peterson BD, Chan C, Katz DH, Tahir UA, Farrell LA, Melander O, Mosley JD, Carr SA, Vasan RS, Larson MG, Smith JG, Wang TJ, Yang Q, Gerszten RE.
Proteomic profiling reveals novel biomarkers and pathways in type 2 diabetes risk.
JCI Insight 2021 Mar 8;6(5):144392
Wei W*, Riley NM*, Yang AC, Kim JT, Terrell SM, Li VL, Garcia-Contreras M, Bertozzi CR, Long JZ.
Cell type-selective secretome profiling in vivo
Nat. Chem. Biol. 2021 Mar;17(3):326-334 *equal contribution
bioRxiv
Press: Nature Methods Research Highlight
2020
Li VL, Kim JT, Long JZ.
Adipose tissue lipokines: recent progress and future directions.
Diabetes 2020 Dec;69(12):2541-2548
Kim JT, Jedrychowski MP, Wei W, Fernandez D, Fischer CR, Banik SM, Spiegelman BM, Long JZ.
A plasma protein network regulates PM20D1 and N-acyl amino acid bioactivity.
Cell Chem. Biol. 2020 Sep 17;27(9):1130-1139
Press: Cell Chemical Biology Preview
Long JZ.
Proteomics illuminates fat as key tissue in aging.
Proc Natl Acad Sci USA 2020 May 12;117(19):10111-10112. (Commentary)
Kim JT, Terrell SM, Li VL, Wei W, Fischer CR, Long JZ.
Cooperative enzymatic control of N-acyl amino acids by PM20D1 and FAAH.
eLife 2020 Apr 9;9:e5521.
Yoo E, Schulze CJ, Stokes BH, Ongoku O, Yeo T, Mok S, Gnädig NF, Zhou Y, Kurita K, Foe IT, Terrell SM, Boucher MJ, Cieplak P, Kumpornsin K, Lee MCS, Linington RG, Long JZ, Uhlemann AC, Weerapana E, Fidock DA, Bogyo M.
The antimalarial natural product salinipostin A identifies essential alpha/beta serine hydrolases involved in lipid metabolism in P. falciparum parasites.
Cell Chem. Biol. 2020 Feb 20;27(2):143-157.
2019
Kim JT, Li VL, Terrell SM, Fischer CR, Long JZ.
Family-wide annotation of enzymatic pathways by parallel in vivo metabolomics.
Cell Chem. Biol. 2019 Nov; 26(11):1623-1629.
Bertholet AM, Chouchani ET, Kazak L, Angelin A, Fedorenko A, Long JZ, Vidoni S, Garrity R, Cho J, Terada N, Wallace DC, Spiegelman BM, Kirichok Y.
H+ transport is an integral function of the mitochondrial ADP/ATP carrier.
Nature 2019 Jul; 571(7766):515-520.
2018
Long JZ, Roche AM, Berdan CA, Louie SM, Roberts AJ, Svensson KJ, Dou FY, Bateman LA, Mina AI, Deng Z, Jedrychowski MP, Lin H, Kamenecka TM, Asara JM, Griffin PR, Banks AS, Nomura DK, Spiegelman BM.
Ablation of PM20D1 reveals N-acyl amino acid control of metabolism and nociception.
Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6937-E6945.
Lin H*, Long JZ*, Roche AM, Svensson KJ, Dou FY, Chang MR, Strutzenberg T, Ruiz C, Cameron MD, Novick SJ, Berdan CA, Louie SM, Nomura DK, Spiegelman BM, Griffin PR, Kamenecka TM.
Discovery of hydrolysis resistant isoindoline N-acyl amino acid analogs that stimulate mitochondrial respiration.
J. Med. Chem. 2018 Apr 12;61(7):3224-3230. *equal contribution
2017
Palmer CJ, Bruckner RJ, Paulo JA, Kazak L, Long JZ, Mina AI, Deng Z, LeClaire KB, Hall JA, Hong S, Zushin PH, Smith KL, Gygi SP, Hagen S, Cohen DE, Banks AS.
Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue.
Mol. Metab. 2017 Oct;6(10):1212-1225.
Vishvanath L, Long JZ, Spiegelman BM, Gupta RK.
Do Adipocytes Emerge from Mural Progenitors?
Cell Stem Cell. 2017 May;20(5):585-586. (Commentary)
2016
Sylow L, Long JZ, Lokurkar IA, Zeng X, Richter EA, Spiegelman BM.
The Cancer Drug Dasatinib Increases PGC-1α in Adipose Tissue but Has Adverse Effects on Glucose Tolerance in Obese Mice.
Endocrinology. 2016 Nov;157(11):4184-4191.
Long JZ, Svensson KJ, Bateman LA, Lin H, Kamenecka T, Lokurkar IA, Lou J, Rao RR, Chang MR, Jedrychowski MP, Paulo JA, Gygi SP, Griffin PR, Nomura DK, Spiegelman BM.
The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria.
Cell. 2016 Jul 14;166(2):424-35.
Press: Science Perspectives; DFCI press; UC Berkeley press; NEJM Clinical Implications of Basic Research; Science Signaling Editor's Choice
Svensson KJ, Long JZ, Jedrychowski MP, Cohen P, Lo JC, Serag S, Kir S, Shinoda K, Tartaglia JA, Rao RR, Chédotal A, Kajimura S, Gygi SP, Spiegelman BM.
A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function.
Cell Metab. 2016 Mar 8;23(3):454-66.
2015
Nass SR, Long JZ, Schlosburg JE, Cravatt BF, Lichtman AH, Kinsey SG.
Endocannabinoid Catabolic Enzymes Play Differential Roles in Thermal Homeostasis in Response to Environmental or Immune Challenge.
J Neuroimmune Pharmacol. 2015 Jun;10(2):364-70.
Zhang Z, Wang W, Zhong P, Liu SJ, Long JZ, Zhao L, Gao HQ, Cravatt BF, Liu QS.
Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity.
Hippocampus. 2015 Jan;25(1):16-26.
2014
Rao RR, Long JZ, White JP, Svensson KJ, Lou J, Lokurkar I, Jedrychowski MP, Ruas JL, Wrann CD, Lo JC, Camera DM, Lachey J, Gygi S, Seehra J, Hawley JA, Spiegelman BM.
Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis.
Cell. 2014 Jun 5;157(6):1279-91.
Schlosburg JE, Kinsey SG, Ignatowska-Jankowska B, Ramesh D, Abdullah RA, Tao Q, Booker L, Long JZ, Selley DE, Cravatt BF, Lichtman AH.
Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout mice.
J Pharmacol Exp Ther. 2014 Aug;350(2):196-204.
Long JZ, Svensson KJ, Tsai L, Zeng X, Roh HC, Kong X, Rao RR, Lou J, Lokurkar I, Baur W, Castellot JJ Jr, Rosen ED, Spiegelman BM.
A smooth muscle-like origin for beige adipocytes.
Cell Metab. 2014 May 6;19(5):810-20.
Press: Cell Metabolism Preview
Zhong P, Wang W, Pan B, Liu X, Zhang Z, Long JZ, Zhang HT, Cravatt BF, Liu QS.
Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling.
Neuropsychopharmacology. 2014 Jun;39(7):1763-76.
2013
Pryce G, Cabranes A, Fernández-Ruiz J, Bisogno T, Di Marzo V, Long JZ, Cravatt BF, Giovannoni G, Baker D.
Control of experimental spasticity by targeting the degradation of endocannabinoids using selective fatty acid amide hydrolase inhibitors.
Mult Scler. 2013 Dec;19(14):1896-904.
Blankman JL, Long JZ, Trauger SA, Siuzdak G, Cravatt BF.
ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC.
Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1500-5.
2012
Wise LE, Long KA, Abdullah RA, Long JZ, Cravatt BF, Lichtman AH.
Dual fatty acid amide hydrolase and monoacylglycerol lipase blockade produces THC-like Morris water maze deficits in mice.
ACS Chem Neurosci. 2012 May 16;3(5):369-78.
Booker L, Kinsey SG, Abdullah RA, Blankman JL, Long JZ, Ezzili C, Boger DL, Cravatt BF, Lichtman AH.
The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice.
Br J Pharmacol. 2012 Apr;165(8):2485-96.
Sticht MA, Long JZ, Rock EM, Limebeer CL, Mechoulam R, Cravatt BF, Parker LA.
Inhibition of monoacylglycerol lipase attenuates vomiting in Suncus murinus and 2-arachidonoyl glycerol attenuates nausea in rats.
Br J Pharmacol. 2012 Apr;165(8):2425-35.
Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Boström EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, Højlund K, Gygi SP, Spiegelman BM.
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.
Nature. 2012 Jan 11;481(7382):463-8.
2011
Nomura DK, Morrison BE, Blankman JL, Long JZ, Kinsey SG, Marcondes MC, Ward AM, Hahn YK, Lichtman AH, Conti B, Cravatt BF.
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation.
Science. 2011 Nov 11;334(6057):809-13.
Long JZ, Cravatt BF.
The metabolic serine hydrolases and their functions in mammalian physiology and disease.
Chem Rev. 2011 Oct 12;111(10):6022-63. (Review)
Long JZ, Cisar JS, Milliken D, Niessen S, Wang C, Trauger SA, Siuzdak G, Cravatt BF.
Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids.
Nat Chem Biol. 2011 Sep 18;7(11):763-5.
Nomura DK, Lombardi DP, Chang JW, Niessen S, Ward AM, Long JZ, Hoover HH, Cravatt BF.
Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer.
Chem Biol. 2011 Jul 29;18(7):846-56.
Ramesh D, Ross GR, Schlosburg JE, Owens RA, Abdullah RA, Kinsey SG, Long JZ, Nomura DK, Sim-Selley LJ, Cravatt BF, Akbarali HI, Lichtman AH.
Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice.
J Pharmacol Exp Ther. 2011 Oct;339(1):173-85.
Kinsey SG, Nomura DK, O'Neal ST, Long JZ, Mahadevan A, Cravatt BF, Grider JR, Lichtman AH.
Inhibition of monoacylglycerol lipase attenuates nonsteroidal anti-inflammatory drug-induced gastric hemorrhages in mice.
J Pharmacol Exp Ther. 2011 Sep;338(3):795-802.
Ezzili C, Mileni M, McGlinchey N, Long JZ, Kinsey SG, Hochstatter DG, Stevens RC, Lichtman AH, Cravatt BF, Bilsky EJ, Boger DL.
Reversible competitive α-ketoheterocycle inhibitors of fatty acid amide hydrolase containing additional conformational constraints in the acyl side chain: orally active, long-acting analgesics.
J Med Chem. 2011 Apr 28;54(8):2805-22.
Kinsey SG, O'Neal ST, Long JZ, Cravatt BF, Lichtman AH.
Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay.
Pharmacol Biochem Behav. 2011 Mar;98(1):21-7.
Long JZ, LaCava M, Jin X, Cravatt BF.
An anatomical and temporal portrait of physiological substrates for fatty acid amide hydrolase.
J Lipid Res. 2011 Feb;52(2):337-44.
2010
Schlosburg JE, Blankman JL, Long JZ, Nomura DK, Pan B, Kinsey SG, Nguyen PT, Ramesh D, Booker L, Burston JJ, Thomas EA, Selley DE, Sim-Selley LJ, Liu QS, Lichtman AH, Cravatt BF.
Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system.
Nat Neurosci. 2010 Sep;13(9):1113-9.
Marrs WR, Blankman JL, Horne EA, Thomazeau A, Lin YH, Coy J, Bodor AL, Muccioli GG, Hu SS, Woodruff G, Fung S, Lafourcade M, Alexander JP, Long JZ, Li W, Xu C, Möller T, Mackie K, Manzoni OJ, Cravatt BF, Stella N.
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors.
Nat Neurosci. 2010 Aug;13(8):951-7.
Kinsey SG, Long JZ, Cravatt BF, Lichtman AH.
Fatty acid amide hydrolase and monoacylglycerol lipase inhibitors produce anti-allodynic effects in mice through distinct cannabinoid receptor mechanisms.
J Pain. 2010 Dec;11(12):1420-8.
Long JZ, Jin X, Adibekian A, Li W, Cravatt BF.
Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases.
J Med Chem. 2010 Feb 25;53(4):1830-42.
Nomura DK, Long JZ, Niessen S, Hoover HS, Ng SW, Cravatt BF.
Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis.
Cell. 2010 Jan 8;140(1):49-61.
2009
Long JZ, Nomura DK, Vann RE, Walentiny DM, Booker L, Jin X, Burston JJ, Sim-Selley LJ, Lichtman AH, Wiley JL, Cravatt BF.
Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo.
Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20270-5.
Straiker A, Hu SS, Long JZ, Arnold A, Wager-Miller J, Cravatt BF, Mackie K.
Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons.
Mol Pharmacol. 2009 Dec;76(6):1220-7.
Pan B, Wang W, Long JZ, Sun D, Hillard CJ, Cravatt BF, Liu QS.
Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signaling.
J Pharmacol Exp Ther. 2009 Nov;331(2):591-7.
Long JZ, Nomura DK, Cravatt BF.
Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism.
Chem Biol. 2009 Jul 31;16(7):744-53.
McQuaid KM, Long JZ, Sames D.
C-H bond functionalization via hydride transfer: synthesis of dihydrobenzopyrans from ortho-vinylaryl akyl ethers.
Org Lett. 2009 Jul 16;11(14):2972-5.
Kinsey SG, Long JZ, O'Neal ST, Abdullah RA, Poklis JL, Boger DL, Cravatt BF, Lichtman AH.
Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain.
J Pharmacol Exp Ther. 2009 Sep;330(3):902-10.
Schlosburg JE, Carlson BL, Ramesh D, Abdullah RA, Long JZ, Cravatt BF, Lichtman AH.
Inhibitors of endocannabinoid-metabolizing enzymes reduce precipitated withdrawal responses in THC-dependent mice.
AAPS J. 2009 Jun;11(2):342-52.
Ahn K, Johnson DS, Mileni M, Beidler D, Long JZ, McKinney MK, Weerapana E, Sadagopan N, Liimatta M, Smith SE, Lazerwith S, Stiff C, Kamtekar S, Bhattacharya K, Zhang Y, Swaney S, Van Becelaere K, Stevens RC, Cravatt BF.
Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain.
Chem Biol. 2009 Apr 24;16(4):411-20.
Long JZ, Li W, Booker L, Burston JJ, Kinsey SG, Schlosburg JE, Pavón FJ, Serrano AM, Selley DE, Parsons LH, Lichtman AH, Cravatt BF.
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects.
Nat Chem Biol. 2009 Jan;5(1):37-44.
Press: Nature Chemical Biology News & Views; ACS Chemical Biology Spotlight; TSRI News & Views; F1000 review
2006
Rhee JM, Pirity MK, Lackan CS, Long JZ, Kondoh G, Takeda J, Hadjantonakis AK.
In vivo imaging and differential localization of lipid-modified GFP-variant fusions in embryonic stem cells and mice.
Genesis. 2006 Apr;44(4):202-18.
2005
Long JZ, Lackan CS, Hadjantonakis AK.
Genetic and spectrally distinct in vivo imaging: embryonic stem cells and mice with widespread expression of a monomeric red fluorescent protein.
BMC Biotechnol. 2005 Jul 4;5:20.